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Fast Viral Detection via SERS and Machine Learning
THE CHALLENGE
The key challenge in developing effective virus detection tools for real-world environments lies in bridging the gap between laboratory-grade accuracy and field-ready usability. Current diagnostic methods like PCR and immunoassay are highly sensitive but depend on complex sample preparation, costly reagents, cold-chain logistics, and...
Published: 5/21/2025
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Updated: 5/21/2025
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Inventor(s): Aditya Garg, Wei Zhou, Peter Vikesland, Linsey Marr, Nisha Duggal
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Engineering
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Chip-integrated Nanolaminate Nano-optoelectrode Arrays for Interfacial Electrochemical Reaction Monitoring
THE CHALLENGE:
In the field of electrochemistry, understanding the dynamics of interfacial reactions is crucial for advancements in areas such as electrocatalysis, biosensing, and energy conversion. Real-time monitoring of these reactions allows scientists to gain insights into mechanisms that drive these processes. Accurate and detailed analysis of...
Published: 5/21/2025
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Updated: 5/21/2025
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Inventor(s): Yuming Zhao, Chuan Xiao, Wei Zhou
Keywords(s):
Category(s): Technology Classifications > Chemicals/Materials
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Transparent NanoplasmonicMeshes for
Bio-interfaced Multimodal Biochemical Sensing
THE CHALLENGE
For multicellular systems such as microbial biofilms and tumors it is essential to capture the holistic system-level spatiotemporal picture. This allows for the understanding of complex and dynamically evolving biological activities to determine effective therapeutic intervention methods. Currently, standard bioanalysis methods do not...
Published: 5/21/2025
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Updated: 5/21/2025
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Inventor(s): Aditya Garg, Wei Zhou, Elieser Mejia
Keywords(s):
Category(s): Technology Classifications > Chemicals/Materials, Technology Classifications, Technology Classifications > Biotechnology
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Multiresonant Plasmonic Meshes for Bio-interfaced
Sensing and Actuation
THE CHALLENGE
Mesh plasmonic devices have the potential to combine the biocompatibility of polymeric meshes with the capabilities of plasmonic nanostructures to enhance nanoscale light-matter interactions for bio-interfaced optical sensing and actuation. However, scalable integration of uniformly structured plasmonic hotspot arrays with polymeric meshes...
Published: 5/21/2025
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Updated: 5/21/2025
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Inventor(s): Aditya Garg, Wei Zhou, Peter Vikesland
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications, Technology Classifications > Biotechnology, Technology Classifications > Chemicals/Materials
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Drug Dosage Testing using Surface-enhanced
Raman Spectroscopy
THE CHALLENGE
Plasmonic nanostructures have enabled label-free surfaceenhanced Raman spectroscopy (SERS) to emerge as a rapid nondestructive molecular fingerprint characterization technique for complex biological samples. However, label-free SERs bioanalysis faces significant challenges in reliability and reproducibility due to local optical field...
Published: 6/4/2025
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Updated: 5/21/2025
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Inventor(s): Wei Zhou, Wonil Nam
Keywords(s):
Category(s): Technology Classifications > Biotechnology
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Washable SERS Fabrics via Micro-Imprinting
THE CHALLENGE
The major challenge in wearable SERS (Surface-Enhanced Raman Spectroscopy) sensors lies in bridging the gap between cutting-edge lab technology and real-world usability. While SERS offers powerful, label-free chemical detection at the molecular level, current fabrication methods rely on expensive clean-room processes, rigid substrates,...
Published: 5/21/2025
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Updated: 5/21/2025
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Inventor(s): Aditya Garg, Wei Zhou
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical
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