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Implant for Plantar Plate Repair
THE CHALLENGE
The plantar plate is a deep fibrocartilaginous structure found in the foot whose primary role is to stabilize metatarsophalangeal joints and other structures; unfortunately, it can tear when inflamed or overworked as a result of running or other activities. Other than pain and discomfort, plantar plate tears can also cause the second...
Published: 7/28/2025
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Updated: 7/28/2025
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Inventor(s): Demitria Poulos, Logan Dickinson, Skye Carlson, Zachary Kozar, Jennifer Wayne, Vincent Wang, John Clements
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Medical Devices
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Robotic Tail Used to Improve Performance and Stability of Mobile Robots
THE CHALLENGE
Natural and man-made disasters are becoming more and more commonplace. As these disasters increase in number, so does the need for, and risk to, first responders who search through rubble and rescue survivors. In response to these increased risks, legged mobile robots have emerged as a first response option as they can maneuver over uneven...
Published: 6/4/2025
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Updated: 6/4/2025
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Inventor(s): Pinhas Ben-Tzvi, Wael Saab, William Rone
Keywords(s):
Category(s): Technology Classifications > Engineering, Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Electronics, Technology Classifications > Medical Devices
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Genomic and Proteomic Biomarkers for Heifer Fertility
THE CHALLENGE
Fertility is a critical factor in livestock breeding, directly impacting the productivity and economic viability of beef and dairy operations. Each year, more than 750,000 beef heifers and 210,000 dairy heifers fail to produce calves despite multiple breeding attempts using artificial insemination or bull exposure. These sub-fertile or...
Published: 6/25/2025
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Updated: 6/3/2025
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Inventor(s): Fernando Biase
Keywords(s):
Category(s): Technology Classifications > Biomedical
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Wireless Acoustofluidic System for Remote Manipulation of Nanoparticles and Cells
THE CHALLENGE:
Acoustofluidics, the integration of acoustic waves with microfluidic systems, plays a crucial role in manipulating particles and cells for applications in biomedical research, diagnostics, and lab-on-a-chip technologies. This technology enables precise control over fluid flow, particle concentration, and cell alignment without physical...
Published: 5/21/2025
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Updated: 5/21/2025
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Inventor(s): Zhenhua Tian, Jiali Li, Luyu Bo, Teng Li
Keywords(s):
Category(s): Technology Classifications > Biomedical
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SonicSurf Manipulator
THE CHALLENGE
Developing advanced contactless manipulation technologies lies in creating a solution that is not only technically effective but also scalable, affordable, and easy to integrate into real-world biomedical and chemical workflows. Current methods—like optical tweezers, magnetic actuators, and traditional acoustic systems—are...
Published: 6/23/2025
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Updated: 5/21/2025
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Inventor(s): Zhenhua Tian, Teng Li, Jiali Li, Luyu Bo
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Chemicals/Materials, Technology Classifications > Engineering
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Organoid-Based Maturation of Liver Stem Cells
THE CHALLENGE
The field of regenerative medicine and drug development urgently requires reliable in vitro liver models that accurately mimic primary human hepatocyte functions. Primary hepatocytes, though ideal for studying liver physiology, suffer from limited availability and high inter-donor variability. Induced pluripotent stem cells (iPSCs) hold...
Published: 6/23/2025
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Updated: 5/21/2025
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Inventor(s): Padmavathy Rajagopalan, Neeti Gandhi
Keywords(s):
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Biomedical
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Infant OPM-MEG Helmet for Measuring Brain Activity
THE CHALLENGE:
Understanding infant brain development is crucial for early detection of neurological disorders and for advancing research in cognitive and sensory development. Neuroimaging technologies enable scientists and clinicians to monitor brain activity, providing insights into how infants' brains respond to various stimuli and interact...
Published: 6/12/2025
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Updated: 5/21/2025
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Inventor(s): Brittany Howell, Megan Evans, Claudia Carreno, Jamie* Holt, Saket Bikmal, Mateo McDermott
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Pharmacology and Therapeutics
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Fast Viral Detection via SERS and Machine Learning
THE CHALLENGE
The key challenge in developing effective virus detection tools for real-world environments lies in bridging the gap between laboratory-grade accuracy and field-ready usability. Current diagnostic methods like PCR and immunoassay are highly sensitive but depend on complex sample preparation, costly reagents, cold-chain logistics, and...
Published: 6/23/2025
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Updated: 5/21/2025
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Inventor(s): Aditya Garg, Wei Zhou, Peter Vikesland, Linsey Marr, Nisha Duggal
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Engineering
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Therapeutic Neutrophils for Cardiovascular Disease
THE CHALLENGE
Treating chronic inflammatory and cardiovascular diseases like atherosclerosis has proven difficult due to the lack of precision in current therapies. While these conditions are driven by complex immune responses, existing treatments rely heavily on broad, systemic anti-inflammatory drugs that often come with unwanted side effects and...
Published: 6/25/2025
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Updated: 5/21/2025
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Inventor(s): Liwu Li, Shuo Geng
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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Neutrophil Subsets for the Treatment of Cancer
THE CHALLENGE
Developing a cancer immunotherapy platform that can effectively and safely leverage the complex role of neutrophils—an abundant, yet highly variable, type of innate immune cell continues to prove challenging. Unlike current therapies that primarily target the adaptive immune system, an approach that must navigate the dual nature...
Published: 6/25/2025
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Updated: 5/21/2025
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Inventor(s): Liwu Li, Yao Zhang
Keywords(s):
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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